Document 0714
 DOCN  M9550714
 TI    Concomitant HIV and mycobacterial infection in Ireland, 1987-92.
 DT    9505
 AU    Mundy LM; Lynch MM; Crowley BD; Kelly G; Desmond NM; Mulcahy FM;
       Department of Genitourinary Medicine, St James's Hospital,; Dublin,
       Ireland.
 SO    Int J STD AIDS. 1994 Nov-Dec;5(6):436-41. Unique Identifier : AIDSLINE
       MED/95151868
 AB    A six-year retrospective review of concomitant HIV and mycobacterial
       infection in the Republic of Ireland is presented. A total of 42 culture
       proven mycobacterial infections were seen in 40 different HIV-infected
       patients. There were 24 infections with Mycobacterium tuberculosis
       (M.tb) and 18 infections with mycobacteria other than tuberculosis
       (MOTT), a significantly higher rate of MOTT infections in Ireland
       compared to a study from 1962-1981. The detection rate for all
       mycobacterial infections had an annual upward trend with a 4-fold
       increase between 1987 and 1992. In homosexuals, MOTT infections occurred
       more frequently than M.tb, while the reverse was true for IVDUs. Twenty
       per cent of the infections were seen in patients recently incarcerated.
       Relapse of tuberculosis occurred in 42.9% (3/7) of non-compliant
       patients, 2 of whom developed rifampin-resistant strains of M.tb. No
       patient compliant to their regimen had a relapse in disease. The overall
       survival of patients after diagnosis of M.tb was significantly better
       than those with MOTT infections, with respective one-year survival rate
       of 79% and 36% (log rank test, P = 0.006).
 DE    Adult  AIDS-Related Opportunistic Infections/DIAGNOSIS/EPIDEMIOLOGY
       Female  Human  HIV Infections/*COMPLICATIONS/*EPIDEMIOLOGY/MORTALITY
       Ireland/EPIDEMIOLOGY  Male  Middle Age  Retrospective Studies
       Tuberculosis/*COMPLICATIONS/DIAGNOSIS/DRUG THERAPY/*EPIDEMIOLOGY
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).