Document 0717
 DOCN  M9550717
 TI    A comparison of AIDS-defining events and subsequent CDC stage IV events
       in IDUs and gay men.
 DT    9505
 AU    Ross JD; Brettle R; Zhu C; Haydon G; Elton RA; Dept. of Genitourinary
       Medicine, Edinburgh Royal Infirmary, UK.
 SO    Int J STD AIDS. 1994 Nov-Dec;5(6):419-23. Unique Identifier : AIDSLINE
       MED/95151865
 AB    The two major risk groups for acquisition of HIV in the UK are gay men
       and IDUs. Individuals from these risk groups vary in a number of
       respects in their life-style, which have the potential to affect the
       course of their HIV disease. This study compares gay men and IDUs from
       the Lothian Region of Scotland with respect to their AIDS defining
       diagnosis and subsequent CDC (Centers for Disease Control) stage IV
       events. Comparisons were made between the two risk groups for their AIDS
       defining diagnosis by performing chi square tests, Mann-Whitney tests
       and logistic regression. Subsequent CDC stage IV events were analysed
       using ordinal logistic regression and Cox regression. 89 IDUs and 56 gay
       men were included in the analysis. Oesophageal candida was a commoner
       AIDS-defining diagnosis in IDUs than gay men and Kaposi's sarcoma was
       diagnosed more frequently in gay men than IDUs. Subsequently oesophageal
       candida was also commoner in IDUs and CMV retinitis was seen more
       frequently in gay men. The role of prophylaxis and differences in diet
       are discussed as possible causes of the observed differences in the
       incidence of oesophageal candida. The higher incidence of CMV retinitis
       in gay men probably reflects the high level of sexual acquisition of
       CMV.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/*DIAGNOSIS  Adult
       AIDS-Related Complex/DIAGNOSIS  AIDS-Related Opportunistic
       Infections/DIAGNOSIS  Comparative Study  *Homosexuality, Male  Human
       Male  Regression Analysis  Risk Factors  Scotland  *Substance Abuse,
       Intravenous  JOURNAL ARTICLE

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