Document 0792 DOCN M9550792 TI [African histoplasmosis: clinical and therapeutic aspects, relation to AIDS. Apropos of 4 cases, including a case with HIV-1-HTLV-1 co-infection] DT 9505 AU Geffray L; Veyssier P; Cevallos R; Beaud B; Mayolle J; Nogier C; Ray E; Thouvenot D; Service de Medecine Interne et Maladies Infectieuses, Centre; Hospitalier de Compiegne, Compiegne. SO Ann Med Interne (Paris). 1994;145(6):424-8. Unique Identifier : AIDSLINE MED/95168732 AB The authors report 4 cases of African histoplasmosis in Zairans. The diagnostic was based ou cutaneous (4 patients), bones (3), lymph-nodes (2), and bowel-localizations (1) and was confirmed by the presence of Histoplasma duboisiis yeasts in cutaneous biopsy (4 patients), in pus of abscess or cutaneous lesions (3) and in stools (1). Two HIV seronegatives patients had a good outcome with amphotericin B. One patient died without any treatment. One HIV-1 and HTLV-1 seropositive patient had successful short-term outcome with ketoconazole. Seven others cases of association between African histoplasmosis and AIDS are noted in the literature. They suggest the opportunistic nature of this deep mycosis. DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS/MICROBIOLOGY Adult *AIDS-Related Opportunistic Infections Case Report English Abstract Female *Histoplasmosis/DIAGNOSIS/THERAPY Human HIV Infections/COMPLICATIONS/MICROBIOLOGY *HIV-1 *HTLV-I Infections/COMPLICATIONS Male Zaire JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASES SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).