Document 0795
 DOCN  M9550795
 TI    Use of thallium-201 brain SPECT to differentiate cerebral lymphoma from
       toxoplasma encephalitis in AIDS patients.
 DT    9505
 AU    Ruiz A; Ganz WI; Post MJ; Camp A; Landy H; Mallin W; Sfakianakis GN;
       Department of Diagnostic Radiology, University of Miami School of;
       Medicine, FL 33136.
 SO    AJNR Am J Neuroradiol. 1994 Nov;15(10):1885-94. Unique Identifier :
       AIDSLINE MED/95168131
 AB    PURPOSE: To determine whether thallium-201 brain single-photon emission
       CT could be used to make the distinction between central nervous system
       lymphoma and toxoplasma encephalitis, which may not be possible by
       routine MR and CT. METHODS: A total of 37 patients with acquired
       immunodeficiency syndrome who had intracranial mass lesions found during
       a 9-month prospective study by either MR or CT underwent further
       evaluation with Tl-201 brain single-photon emission CT. RESULTS: Twelve
       patients had increased intense focal Tl-201 uptake. All of these
       patients had either biopsy- or autopsy-proven lymphoma. Twenty-five of
       the patients studied had no Tl-201 brain uptake in the lesion(s); 24 of
       these patients had toxoplasma encephalitis on clinical follow-up. One
       patient with no Tl-201 uptake was found by cerebrospinal fluid analysis
       to have mycobacterium tuberculosis abscess. CONCLUSION: Patients with
       acquired immunodeficiency syndrome who have intracranial mass lesions on
       MR or CT may benefit from Tl-201 brain single-photon emission CT because
       it can help distinguish between lymphoma and infectious lesions such as
       toxoplasma encephalitis.
 DE    Adult  AIDS Dementia Complex/*RADIONUCLIDE IMAGING  AIDS-Related
       Opportunistic Infections/*RADIONUCLIDE IMAGING  Brain
       Neoplasms/*RADIONUCLIDE IMAGING  Comparative Study  Diagnosis,
       Differential  Female  Human  Image Processing, Computer-Assisted
       Lymphoma, AIDS-Related/*RADIONUCLIDE IMAGING  Magnetic Resonance Imaging
       Male  Middle Age  Prospective Studies  Thallium Radioisotopes/DIAGNOSTIC
       USE  Tomography, Emission-Computed, Single-Photon/*METHODS  Tomography,
       X-Ray Computed  Toxoplasmosis, Cerebral/*RADIONUCLIDE IMAGING  JOURNAL
       ARTICLE

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